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Cancer Stem Cells, Immunotherapy. An Intergrated Approach to Cancer Treatment

Автор:  Obdulio P.
мягкая обложка
100 страниц
2009 год
Издательство:  Книга по Требованию
Цена:
2005 руб
отсутсвует
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Описание:This understanding promises to deliver novel therapeutic agents that will eliminate the burden of the disease on individuals, families and society. These cells possess properties of normal stem cells and are typically less responsive to current therapies, thus explaining the observed resistance. This book uses FLT3 as an example to illustrate the development of targeted therapeutics, mechanisms of resistance and strategies to overcome resistance. Recent studies strongly support the notion that at least some cancers are initiated, maintained and disseminated by cancer stem cells. Our knowledge of cancer initiation, progression and treatment has dramatically increased over the last decade. A number of aberrantly activated proteins have been found critical for the proliferation and/or survival of cancer stem cells, one of which is the mutant FLT3 receptor, expressed on leukemia stem cells. Based on the cancer stem cell theory, the elimination of these cancer stem cells is imperative if we are to cure patients. However, early impressive clinical results are often overshadowed by relapse and the development of resistance.


Orthomol Immun Junior Сила иммунитета на страже Вашего ребенка Orthomol Immun Junior Сила иммунитета на страже Вашего ребенка

2990 руб
Бесплатная доставка


The Language of the Genes

One form of the gene for a protein called alpha-i anrrypsin much increases the risk of emphysema among smokers. The incidence of those with two copies is around one in five thousand; and half of all smokers unlucky enough to fall into that group die younger than forty, whereas the lifespan for gene carriers who do not smoke is extended by twenty years. To discover one's individual danger concentrates the mind: and in Sweden one in ten teenagers with the high-risk genotype smokes, compares to a fifth of others. To assess future health is not new. All doctors check their patients for high blood pressure and healthy women are examined for signs of breast cancer. As technology advances, signs of other cancers (such as prostate cancer, which generates antigens in the urine) can be checked long before symptoms appear. DNA will make diagnosis easier, with tests for a wide variety of diseases, either inherited or the result of mutations in body cells themselves. Once a patient or someone worried about a family problem turns up, DNA is just another weapon in the doctor's armoury ...»

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Счётный материал "Овощи", арт. Р45/788.
При обучении детей счету, очень полезно использовать красивый, яркий и разнообразный счетный материал. Ребенку очень сложно мыслить
326 руб
Раздел: Счетные наборы, веера
Папка-сумка "Фиксики", с ручками, 35x4x26 см.
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339 руб
Раздел: Папки-портфели, папки с наполнением
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581 руб
Раздел: Демонстрационные рамки, планшеты, таблички


Cancer Stem Cell Features In Established Melanoma Cell Lines. Developing a cancer stem cell model in melanoma cell lines
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Fabricating Brain Tissue by growing Stem Cells on Coral Skeletons. Stem cells convert into neurons and glia when cultivated on three-dimensional aragonite crystalline matrix
The brain has a limited ability to recover from injury; however, the discovery of stem cells that can differentiate into neural cells – neurons and glia - creates conditions for generation of new cells to replace the damaged tissue.
          2005 руб             2009 год          60 стр.          мягкая обложка

Microchimeric Fetal Stem cells in Pregnancy. MSc dissertation to University of London
A true stem cell is a primitive cell capable of unlimited cell cycles with the capacity to cease being a stem cell and become one of a wide variety of specialized cells that can no longer divide Fetal stem cells cross into maternal blood during pregnancy and thus represent a potential non- invasive source of foetal genetic material for prenatal diagnosis.
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Effects of Naturally Occurring Compounds on Human Cancer Cells. Anticancer Activity of Resveratrol, Piceatannol, Gallic Acid
The aim of this thesis was to investigate the biochemical and cytotoxic effects of naturally occurring compounds, such as resveratrol, resveratrol analogs, piceatannol, gallic acid, Avemar, and heavy water alone and/or in combination with clinically established anticancer agents such as arabinofuranosylcytosine and gemcitabine.
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Recombinant Antibodies for Cancer Immunotherapy. Tools for Breast Cancer Detection and Therapy Recombinant Anti-MUC1 and Anti-ErbB2 Antibodies:
The discovery of the tumor markers, opened a new era in the development of antibody-targeted cancer therapy.
          2781 руб             2009 год          200 стр.          мягкая обложка

The Force in Biology. Understanding and Measuring the Role of Cell Mechanics in Cancer and Aging
A few important questions remain: 1) what are the corresponding mechanical changes, 2) how do these mechanical changes help the cell adapt, 3) is it possible these adaptations result in unforeseen consequences, and 4) if so, do they result in disease? Due to technical limitations, only a portion of the answers have been explored to date. In an attempt to answer these questions, we present studies that use novel insights to quantify changes in cell and nuclear mechanics and reveal the potential impact forces play in cancer and aging. Mechanical adaptations in response to forces have been studied mainly though visualization of changes in cytoskeletal structures and understanding the corresponding signaling pathways. These observations are informative in elucidating regulating proteins and cellular phenotype, but do not offer insights to the effects, or cell mechanics, of these cellular changes and regulations. Understanding forces in the context of biology is essential as all cells in the human body are constantly subjected to mechanical forces and are often presented with situations where adaptations are critical for survival.
          2781 руб             2008 год          172 стр.          мягкая обложка

Possible therapeutic effect in lung cancer Inhibition by Curcuma longa extract. Telomerase in A549 cell line:
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Tropic of Cancer (на англ.яз.)
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The detection of breast masses in temporal mammographic pairs is also investigated.
          3188 руб             2009 год          260 стр.          мягкая обложка

Platinum Porous Electrodes for Fuel Cells. with focus on Proton Exchange Membrane Fuel Cells (PEMFCs)
Fuel cell energy bears the merits of renewability, cleanness and high efficiency.
          3188 руб             2009 год          208 стр.          мягкая обложка

Running Raw in the Wild The Cancer Emails.
There were days of despair and days of light. Cancer! The diagnosis used to be a death sentence!
          3188 руб             2008 год          296 стр.          мягкая обложка

Comparing cancer survival using population-based cancer registry data. methods and applications
Interpretation of comparative survival from population-based cancer registry data is generally not easy.
          2400 руб             2009 год          140 стр.          мягкая обложка

Toxic emissions and devaluated CO2-neutrality. Expanded combustion of stem wood violates Sustainable Development
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Linking Cells from the Immune System with Bone Cells The Role of Regulatory T Cells in Bone Homeostasis.
This principle appears conceivable, because activation of the immune system and activation of bone resorption may go hand in hand.
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Cancer cells display characteristic traits acquired in a step-wise manner during carcinogenesis.
          3618 руб             2010 год          196 стр.          мягкая обложка

An Experimental Study of Catalytic and Non-Catalytic Reaction in Heat Recirculating Reactors and Applications to Power Generation Swiss Roll Heat Exchangers/Reactors and Solid-Oxide-Fuel-Cells Power Generation.
An experimental study of the performance of a Swiss roll heat exchanger and reactor was conducted, with emphasis on the extinction limits and comparison of results with and without catalyst.
          1994 руб             2008 год          100 стр.          мягкая обложка

Search for Breast Cancer Susceptibility Genes. The Growth Hormone-1 / Insulin-like Growth Factor-1 Pathway and its Relationship to Breast Cancer
The work in this dissertation summarizes the investigation of polymorphisms in the GH1/IGF-1 axis in relation to breast cancer risk by means of the planning and conducting of case-control studies.
          2413 руб             2008 год          132 стр.          мягкая обложка

Ab-Initio Modelling of Electrochemistry. Application to Proton-Exchange-Membrane Fuel Cells
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          3231 руб             2008 год          240 стр.          мягкая обложка

Access to Cancer Education and Screening. A Long and Difficult Journey for Chinese Immigrants in New York City
Findings revealed that the concept of “prevention” in the Chinese culture was based on holistic views of health and yin-yang balance principles.
          2781 руб             2009 год          196 стр.          мягкая обложка

Electrocatalysts for PEM Fuel Cells. Synthesis, Characterization, and Performance Testing
It could serve as a valuable resource for better understanding of the most current state of electrocatalysis research on low temperature PEM fuel cells.
          2005 руб             2008 год          120 стр.          мягкая обложка

Medical Staff-Family Health Communication in Cancer. Psychometric, Model and Mediational Testing
This book extends our knowledge of medical staff-family health communication in cancer by examining the relations between communication and psychological variables.
          2005 руб             2009 год          72 стр.          мягкая обложка

Consumers of Internet Health Information. Psychological Impact Among Women with Breast Cancer
This book is about the experience of women with breast cancer who searched the Internet for information.
          2005 руб             2009 год          80 стр.          мягкая обложка

Biopharmaceuticals. A Study of Apoptosis and Cell Cycle to Augment Transfection Efficiency in Chinese hamster ovary (CHO) Cells
The host required is not only required to produce the desired product, but also needs to demonstrate robustness in a bioreactor system.
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The individual tree growth and yield models, such as stem taper, volume, biomass and height growth, play an important role in forest growth and yield prediction and projection systems.
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The Metastasis Suppressor: Ndrg-1. Examining the Molecular Function and Iron Regulation of Ndrg-1 in Cancer
Furthermore, the ability of novel anti-cancer agents, the iron chelators, to up- regulate Ndrg-1 was also explored.
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A Suicide Vector Design for Cells Expressing HIV-1 Regulatory Genes. Basics, Methods, Handicaps
In order to prevent leaky gene expression stemming from the basal gene expression from LTR even if it was not induced by Tat, and thereby having potential to damage healthy cells, the prerequisite cis-acting DNA sequences were cloned downstream of the toxic gene.
          2413 руб             2009 год          136 стр.          мягкая обложка

VIP PROTECTS TH2 CELLS BY DOWNREGULATING GRANZYME B EXPRESSION
However, regardless of the initial Th1/Th2 balance, the final immune response depends to a large degree on the regulation of Th1 or Th2 survival under specific conditions.
          2413 руб             2008 год          132 стр.          мягкая обложка

Life after cancer. - a registry-based study of social and economic consequences of cancer in Norway
This the largest study to date on sociodemographic outcomes in a complete population of cancer survivors, utilizing high quality registry data.
          2413 руб             2010 год          144 стр.          мягкая обложка

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