Numerical modeling of blood flow in human left coronary artery and in vitro study of endothelial cell activation by shear stress Estimation of coronary wall shear and endothelial cell activation.

Myeloid, or blood cell-forming tissue, is found in the bone marrow and provides the stem cells that develop into erythrocytes, granulocytes, agranulo-cytes, and platelets. Red marrow is characterized by active hematopo-iesis; yellow bone marrow is inactive and contains mostly fat cells. In the human adult, hematopoiesis takes place in the mar row of the flat bones of the skull, ribs and sternum, the vertebral column, the pelvis, and the proximal ends of some long bones. Erythropoiesis is the process of RBC formation. Bone marrow stem cells (colony-forming units, CFUs) differentiate into proerythroblasts under the influence of the glycoprotein erythropoietin, which is produced by the kidney. Proerythroblast is a large basophilic cell containing a large spherical euchromatic nucleus with prominent nucleoli. Basophilic erythroblast is a strongly basophilic cell with nucleus that comprises approximately 75% of its mass. Numerous cytoplasmic polyribosomes, condensed chromatin, no visible nucleoli, and continued hemoglobin synthesis characteristics of this cell ...»