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Experimental approaches in diabetic cataract research. - - - - - - - - - - - - - - - - - - - - - - - - - The role of hyperglycemia-induced oxidative stress in eye lens proteins modification

Автор:  Zuzana K.
мягкая обложка
108 страниц
2009 год
Издательство:  Книга по Требованию
Цена:
1994 руб
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Описание:Cataract, the opacification of eye lens, is leading cause of blindness worldwide. Besides oxidative stress, taking into consideration additional mechanisms of cataractogenesis (non-enzymatic glycation, polyol pathway, calpains involvement), it has further directed the intentional synthesis of new derivatives of the pyridoindole stobadine to prevent diabetic complications. Diabetic patients have 25 times higher risk of cataract onset as non-diabetics. The results indicated an actual prospect of pharmacological utilization of antioxidants in prevention of diabetic cataract. Usually is treated surgically, however biochemical solution or pharmacological intervention that would maintain the transparency of the lens is desirable. Study was focused on the investigation of oxidative mechanisms of eye lens proteins injury under model conditions in vitro and in vivo. Book represents handy tool counting experimental approaches thus is highly recommended to entire physiology, biochemistry and pharmacology oriented audience: students, research associates, medical doctors or simply to knowledgeable public willing to reveal the fundamentals of diabetic cataract formation.


Orthomol Immun Junior Сила иммунитета на страже Вашего ребенка Orthomol Immun Junior Сила иммунитета на страже Вашего ребенка

2990 руб
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Большая Советская Энциклопедия (МА)

Сыграл большую роль в установлении и развитии экономических и научных связей между Индией и СССР. Иностранный член АН СССР (1958), член Лондонского королевского общества (1945).   Соч.: Some observations on the process of the growth of national income, [Calcutta, 1953]; Talks on planning, Bombay-Calcutta, [1961]; The approach of operational research to planning in India, Bombay-Calcutta, [1963]; в русском переводе — Выборочные обследования в Индии. (Новый опыт Индийского статистического института), перевод с английского, М., 1958. Махалин Алексей Ефимович Маха'лин Алексей Ефимович [10(23).3.1908, село Новокрежи, ныне село Махалино Кузнецкого района Пензенской области, — 29.7.1938], Герой Советского Союза (25.10.1938), лейтенант. Член КПСС с 1932. Родился в семье крестьянина. С 1930 в пограничных войсках, был помощником начальника заставы Хасанского пограничного отряда. 29 июля 1938 личный состав пограничной заставы вступил в бой с ротой японцев у сопки Безымянная в районе острова Хасан и несколько часов до подхода подкрепления героически сдерживал натиск врага. М. погиб в рукопашной схватке ...»

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